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Cambridge University
John van Geest Centre for Brain Repair
E.D. Adrian Building
Forvie Site, Robinson Way
Cambridge, CB2 0PY, UK
Cambridge University website
Prof. Roger Barker team website
The Cambridge Centre for Brain Repair is part of the Department of Clinical Neurosciences, University of Cambridge. The ultimate aim of work in the Centre is to understand, and eventually to alleviate and repair damage to the brain and spinal cord which results from injury or neurodegenerative disease. At the centre, an examination of Parkinson’s disease patients occurs in a number of ways. The clinic uses various tools in order to fully assess the nature of the disease such as computer tests for memory, eye movement recordings, drug trials as well as collaborating on brain imaging studies.
Prof. Roger Barker
Xiaoling He
Pamela Tyers
Natalie Valle Guzman
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Freiburg University
Dept. of Stereotactic Neurosurgery
Laboratory of Molecular Neurosurgery
University of Freiburg – Neurocentre
Breisacher Strasse 67
D-79106 Freiburg, Germany
Freiburg University website
Department of Stereotactic Neurosurgery website
The group investigates the mechanisms of functional and behavioural restoration in neurodegenerative diseases such as Parkinson's (PD) or Huntington's diseases (HD). Currently, they are working on stem cell- or progenitor cell-based therapies both in the animal model and in human trials.
PD Dr. Christian Winkler
Dr. Tobias Piroth
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Cardiff University
School of Biosciences
Brain Repair Group
Life Sciences Building
Museum Avenue
Cardiff CF10 3AX, UK
Cardiff University website
The Brain Repair Group is working to understand and develop new cell based treatments for major neurodegenerative diseases of the brain, in particular Huntington's disease and Parkinson's disease. They are seeking to develop new strategies for therapy based on a multidisciplinary approach in several converging problems.
Prof. Steve Dunnett
Prof. Anne Rosser
Administration: Anne-Marie McGorrian
Dr. Kathryn Peall
Dr. Alistair Church
Ngoc-Nga Vinh
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Lund University
Department of Experimental Medical Science
Lund University, 221 84 Lund, Sweden
Lund University website
Neurobiology Unit
Neurobiology Unit website
Research or the group aims at developing new restorative and neuroprotective treatments for neurodegenerative diseases using cell transplantation and direct in vivo gene delivery. Additionally, we explore rodent models of Parkinson´s disease to study the mechanisms underlying development of L-DOPA-induced dyskinesias, and use recombinant viral vectors as tools to model Parkinson-like neurodegeneration in rodents, and for delivery of putative therapeutic factors, GDNF and Nurr 1 in particular, to the brain.
Prof. Anders Björklund
Jenny Nelander
Prof. Malin Palmar - Developmental and Regenerative Neurobiology Lab
Neuronal Survival Unit
Neuronal Survival Unit website
The group’s mission is to understand neurodegenerative diseases and develop new therapies that are of benefit to patients and their caregivers. Their research is focused on pathogenetic mechanisms and pharmacological treatment in cell and animal models of Parkinson’s and Huntington’s diseases. Cell replacement therapy with stem cells in attempts to repair brains in animal models of Parkinson’s and Huntington’s diseasesm is also being examined.
Prof. Patrik Brundin
Laboratory of Neurogenesis and Cell Therapy
Laboratory website
The group is developing novel strategies for the treatment of neurological disorders (e.g. Parkinson’s Disease) based on cell transplantation and gene therapy with the general aim to repair and protect the brain. First clinical trials aiming to protect against the degeneration of dopamineneurons in Parkinson’s patients are also planed.
Prof. Olle Lindvall
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Imperial College London
Neurosciences and Mental Health
South Kensington Campus
London SW7 2AZ UK
Imperial College website
Prof. Paola Piccini website
Use of functional imaging, principally positron emission tomography (PET), to identify the functional anatomy underlying control of different aspects of limb movement in normal subjects is the main research focus of the group. With this approach they are studying dopaminergic function in Parkinson’s disease (PD) kindreds with a genetic mutation and to measure the effects of neuroprotective and restorative therapies on rates of disease progression in PD and Huntington’s disease.
Prof. Paola Piccini
Nick Lao-Kaim
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University College London
Institute of Neurology
Unit of Functional Neurosurgery
Box 146
National Hospital for Neurology & Neurosurgery
London WC1N 3BG, UK
University College website
The group is examining the use of the Deep Brain Stimulation technique to help understand differences in treatment response in Parkinson’s disease suffering patients. By studying the genetic variations that influence the sufferer’s response, they hope to develop treatments that will work for all individuals with Parkinson’s.
Prof. Thomas Foltynie
Dr. Viswas Dayal
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Skane University Hospital
SE-205 02 Malmö, Sweden
Skane University website
Prof. Widner and his group has since 15 years pioneered the field of cell transplantation in Parkinson's disease, and has been involved in clinical assessment of patients with this disease and other movement disorders. He has also worked for many years with animal models of movement disorders and the development of new restorative and neuroprotective strategies.
Prof. Hakan Widner
Dr. Hjalmar Bjartmarz
Dr. Gesine Paul
Jan Reimer
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Life Science Governance Institute
Schottenfeldg. 29, 1070 Vienna, Austria
LSGI website
The "Life-Science-Governance" Institute (LSGI) focuses on the relationship between governance and the life sciences. It addresses the interrelated topics of governance through and of the life sciences. The institutes work involves contemporary life science governance, and develops solutions for good life science governance.
Prof. Herbert Gottweis - passed away in March 2014.
Dr. Paul Just
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ASSISTANCE PUBLIQUE – HOPITAUX DE PARIS
Hôpital Henri Mondor
51, av. Du Maréchal de Tassigny
94010 Créteil – Paris, France
APHP website
Dr. Philippe Remy
Dr. Stéphane Palfi
Hélène Lepetit
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INSERM-ECRIN
ECRIN website
INSERM website
The European Clinical Research Infrastructures Network (ECRIN) is a sustainable, not-for-profit infrastructure supporting multinational clinical research projects in Europe. ECRIN provides information, consulting and services to investigators and sponsors in the preparation and in the conduct of multinational clinical studies, for any category of clinical research and in any disease area. This is particularly relevant for investigator-initiated or small and medium enterprise-sponsored clinical trials and for clinical research on rare diseases where international cooperation is a key success factor.
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Inomed
Inomed Medizintechnik GmbH
Tullastrasse 5a, 79331 Teningen, Germany
Inomed website
Inomed is a medical technology company, operating internationally, which develops nerve protection instruments and systems for precisely targeted patient treatment. Working with doctors and users, inomed develops new tools and methods in the fields of intraoperative neuromonitoring, neurosurgery, pain therapy and neurological diagnostics. Inomed supplies high-quality products to improve treatment outcomes, and uses innovative technologies to ensure safety for both treatment providers and patients.
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Life Technologies Limited, part of Thermo Fischer Scientific
3 Fountain Drive, Paisley PA4 9RF, UK
Life Technologies website
Life Technologies is a global biotechnology tools company providing premier systems, consumables, and services for scientific researchers around the world. Life Technologies customers conduct their research across the biological spectrum, working to advance personalized medicine, regenerative science, molecular diagnostics, agricultural and environmental research, and 21st-century forensics.
Dr. Roland Leathers
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Cambridge Cognition
Tunbridge Court, Tunbridge Lane,
Bottisham, Cambridge CB25 9TU, UK
Cambridge Cognition website
Cambridge Cognition is a neuroscience digital health company specialising in the precise measurement of clinical outcomes in neurological and psychiatric disorders. The Company develops and markets validated near patient assessment products using cognition as a biomarker to improve the research, diagnosis and treatment of conditions such as Parkinson's, Alzheimer's and schizophrenia. Partners include the world's leading biotechnology and pharmaceutical companies, academic institutions and public-private health organisations.
Dr. Jennifer Barnett
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Imanova Ltd
Burlington Danes Building
Imperial College London
Hammersmith Hospital
Du Cane Road
London, W12 0NN, UK
Imanova website
Imanova is an innovative alliance between the UK's Medical Research Council and three world-class London Universities: Imperial College, Kings College and University College. Established in April 2011 as an independent company, Imanova and its partners bring together a breadth and depth of knowledge and expertise that will drive research and innovation in imaging sciences. Imanova will have a real impact on human health and the understanding of disease. Imanova now owns and manages the renowned Clinical Imaging Centre (CIC) located at Imperial College London's Hammersmith Hospital campus. This state of the art facility was developed by former owner GlaxoSmithKline, and has benefitted from £47million of investment in equipment and infrastructure since opening in 2007.
Dr. Kevin Cox
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